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Cortisol, prenisolone與皮質醇強度劑量換算表

Cortisol 參考值:

AM8~9點:5~20ug/dl
PM4~5點:3~10ug/dl

cortisol 濃度具有生物時鐘特性,會隨著每日的時間而改變。因此測定cortisol必須定時採血(上午八點或下午四點), 以方便正常參考值比對。測定血清cortisol常使用於腎上腺功能不足的患者,並常和ACTH搭著, 診斷愛迪生氐症(Addison''s disease:cortisol分泌過少的疾病)及庫欣氐症候群(Cushing''s syndrome :cortisol分泌過量的疾病)。 對於使用類固醇治療的患者,可用來評估腎上腺分泌功能被藥物壓抑的程度。

http://www.symcl.com.tw/check_single.php?tno=B&sno=122

Conversion Data

GlucocorticoidApproximate Equivalent dose (mg)Half-life (Biologic) hours
Short-Acting
Cortisone   258-12
Hydrocortisone   208-12
Intermediate-Acting
Methylprednisolone418-36
Prednisolone518-36
Prednisone518-36
Triamcinolone418-36
Long-Acting
Betamethasone0.6 - 0.7536-54
Dexamethasone0.7536-54

(劑量換算表 叁考)

----------------------------------------------------------------------------
Glucocorticoid | Equivalent dose (mg) | Half-life (Biologic) hours 
-----------------------------------------------------------------------------
Short-Acting 
-----------------------------------------------------------------------------
   Cortisone                25                       8-12 
Hydrocortisone           20                       8-12 
-----------------------------------------------------------------------------
Intermediate-Acting 
-----------------------------------------------------------------------------
Methylprednisolone     4                        18-36 
Prednisolone               5                        18-36 
Prednisone                  5                       18-36 
Triamcinolone              4                       18-36 
-----------------------------------------------------------------------------
Long-Acting 
-----------------------------------------------------------------------------
Betamethasone          0.6 - 0.75            36-54 
Dexamethasone          0.75                    36-54 
-----------------------------------------------------------------------------

calculator link: https://wwwv.tsgh.ndmctsgh.edu.tw\files\web\192\contents\10027\corticocalc.htm


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