1

Emergency SARS-CoV-2 Variants of Concern: Novel Multiplex Real-Time RT-PCR Assay for Rapid Detection and Surveillance

Microbiol Spectr. 2022 Feb 23;10(1):e0251321.doi: 10.1128/spectrum.02513-21. Epub 2022 Feb 23.

Chih-Hung Wang et al

2

Federated learning for predicting clinical outcomes in patients with COVID-19

Nat Med. 2021 Oct;27(10):1735-1743.doi: 10.1038/s41591-021-01506-3. Epub 2021 Sep 15

Chih-Hung Wang et al

3

Synergistic effects of combined treatment with ultrasound-mediated cisplatin-loaded microbubbles and atorvastatin on head and neck cancer

Head Neck. 2021 Jan;43(1):15-26.doi: 10.1002/hed.26445. Epub 2020 Sep 21.

Ai-Ho Liao, Wan-Ting Lin, Hang-Kang Chen, Cheng-Ping Shih, Chih-Hung Wang, Yuen-Hsiang Chu 

4

In Vivo Automatic and Quantitative Measurement of Adult Human Larynx and Vocal Fold Images

J Voice. 2021 Jun 24;S0892-1997(21)00138-7.doi: 10.1016/j.jvoice.2021.04.003. Online ahead of print.

Chung-Feng Jeffrey Kuo, Chun-Shu Lin, Kai-Yao Chiang, Jagadish Barman, Shao-Cheng Liu

5

Impact of the COVID-19 Pandemic on the Loading and Quality of an Emergency Department in Taiwan: Enlightenment from a Low-Risk Country in a Public Health Crisis

J Clin Med. 2021 Mar 10;10(6):1150.doi: 10.3390/jcm10061150.

Jamie Yu-Hsuan Chen, Feng-Yee Chang, Chin-Sheng Lin, Chih-Hung Wang, Shih-Hung Tsai, Chia-Cheng Lee, Sy-Jou Chen

6

Antidepressants and risk of sudden sensorineural hearing loss: a population-based cohort study

Int J Epidemiol. 2021 Nov 10;50(5):1686-1697.doi: 10.1093/ije/dyab023.

Pei-Xun Zhong, I-Hsun Li, Jui-Hu Shih, Chin-Bin Yeh, Kuan-Wei Chiang, Li-Ting Kao

7

Clinical Relevance of Urine Flow Rate and Exposure to Polycyclic Aromatic Hydrocarbons

Int J Environ Res Public Health. 2021 May 18;18(10):5372.doi: 10.3390/ijerph18105372.

Po-Hsuan Jeng, Tien-Ru Huang, Chung-Ching Wang, Wei-Liang Chen

8

Quantitative laryngoscopy with computer-aided diagnostic system for laryngeal lesions

Sci Rep. 2021 May 12;11(1):10147.doi: 10.1038/s41598-021-89680-9.

Chung Feng Jeffrey Kuo, Wen-Sen Lai, Jagadish Barman, Shao-Cheng Liu

9

Multi-Omics Data Analysis of Gene Expressions and Alterations, Cancer-Associated Fibroblast and Immune Infiltrations, Reveals the Onco-Immune Prognostic Relevance of STAT3/CDK2/4/6 in Human Malignancies

Cancers (Basel). 2021 Feb 25;13(5):954.doi: 10.3390/cancers13050954.

Bashir Lawal, Li-Ching Lin, Jih-Chin Lee, Jia-Hong Chen, Tanios S Bekaii-Saab, Alexander T H Wu, Ching-Liang Ho

10

Solitary neurofibroma in the external auditory canal

Ear Nose Throat J. 2021 Oct 2;1455613211048978.doi: 10.1177/01455613211048978.

Pei-Rong Lee, Hsin-Chien Chen

11

Inhibition of Cochlear HMGB1 Expression Attenuates Oxidative Stress and Inflammation in an Experimental Murine Model of Noise-Induced Hearing Loss

Cells. 2021 Apr 5;10(4):810.doi: 10.3390/cells10040810.

Cheng-Ping Shih, Chao-Yin Kuo, Yuan-Yung Lin, Yi-Chun Lin, Hang-Kang Chen, Hao Wang, Hsin-Chien Chen, Chih-Hung Wang

12

Adipose-derived stem cell induced-tissue repair or wound healing is mediated by the concomitant upregulation of miR-21 and miR-29b expression and activation of the AKT signaling pathway

Arch Biochem Biophys. 2021 Jul 15;705:108895. doi: 10.1016/j.abb.2021.108895. Epub 2021 Apr 30.

Shao-Cheng Liu, Oluwaseun Adebayo Bamodu, Kuang-Tai Kuo, Iat-Hang Fong, Chih-Cheng Lin, Chi-Tai Yeh, Shyi-Gen Chen

13

Genetic Variants of lncRNA GAS5 Are Associated with the Clinicopathologic Development of Oral Cancer

J Pers Med. 2021 Apr 26;11(5):348.doi: 10.3390/jpm11050348.

Ming-Hong Hsieh, Hsueh-Ju Lu, Chiao-Wen Lin, Chia-Yi Lee, Shang-Jung Yang, Pei-Hsuan Wu, Mu-Kuan Chen, Shun-Fa Yang

14

Illegal Drug Use and Risk of Hearing Loss in the United States: A National Health and Nutrition Examination Survey

Int J Environ Res Public Health. 2021 Nov 13;18(22):11945.doi: 10.3390/ijerph182211945.

Po-Ting Lin, I-Hsun Li, Hui-Wen Yang, Kuan-Wei Chiang, Chih-Hung Wang 6, Li-Ting Kao

15

The Immediate and Long-Term Impact of Military Aircraft Noise on Hearing: A Cross-Sectional Comparison of Fighter Pilots and Ground Staff

Int J Environ Res Public Health. 2021 Mar 14;18(6):2982.doi: 10.3390/ijerph18062982.

Chao-Yin Kuo, Chia-Lien Hung, Hsin-Chien Chen, Cheng-Ping Shih, Rou-Huei Lu, Chen-Wai Chen, Li-Wen Hung, Yi-Chun Lin, Hang-Kang Chen, Da-Ming Chu, Yuan-Yung Lin, Yueh-Chun Chen, Chih-Hung Wang

16

Efficacy of combined canalith-repositioning procedure and supine to prolonged lateral position in treating posterior canal benign paroxysmal positional vertigo

Auris Nasus Larynx. 2021 Oct;48(5):834-840.doi: 10.1016/j.anl.2021.01.009. Epub 2021 Jan 17.

Che-Jui Lee, Chia-Yi Lee, Pei-Hsuan Wu, Chih-Hung Wang, Hsin-Chien Chen, Cheng-Ping Shih

17

Clinical characteristics and correlation between hearing outcomes after different episodes of recurrent idiopathic sudden sensorineural hearing loss

Auris Nasus Larynx. 2021 Oct;48(5):870-877.doi: 10.1016/j.anl.2021.01.021. Epub 2021 Feb 4.

Pei-Hsuan Wu, Chia-Yi Lee, Hsin-Chien Chen, Jih-Chin Lee, Yueng-Hsiang Chu, Li-Hsiang Cheng, Chih-Hung Wang, Cheng-Ping Shih

18

Inhibition of Bruton's tyrosine kinase as a therapeutic strategy for chemoresistant oral squamous cell carcinoma and potential suppression of cancer stemness

Oncogenesis. 2021 Feb 27;10(2):20.doi: 10.1038/s41389-021-00308-z.

Shao-Cheng Liu, Yang-Che Wu, Chih-Ming Huang, Ming-Shou Hsieh, Ting-Yi Huang, Chin-Sheng Huang, Tung-Nien Hsu, Mao-Suan Huang, Wei-Hwa Lee, Chi-Tai Yeh, Chun-Shu Lin

19

Isoorientin inhibits epithelial-to-mesenchymal properties and cancer stem-cell-like features in oral squamous cell carcinoma by blocking Wnt/β-catenin/STAT3 axis

Toxicol Appl Pharmacol. 2021 Aug 1;424:115581.doi: 10.1016/j.taap.2021.115581. Epub 2021 May 18.

Shao-Cheng Liu, Chin-Sheng Huang, Chih-Ming Huang, Ming-Shou Hsieh, Mao-Suan Huang, Iat-Hang Fong, Chi-Tai Yeh, Chih-Cheng Lin

20

The correlation between neonatal parameters and late-onset inner ear disorders in congenital cytomegalovirus infection: a 10-year population-based cohort study

Clin Otolaryngol. 2022 Jan;47(1):107-114. doi: 10.1111/coa.13864. Epub 2021 Sep 28.

Pei-Hsuan Wu, Chia-Yi Lee, Jing-Yang Huang, Shun-Fa Yang, Cheng-Ping Shih

21

Combined Acupuncture-Hyperbaric Oxygen-Steroids Therapy for Idiopathic Sudden Sensorineural Hearing Loss: A Retrospective Observational Study

J Altern Complement Med. 2021 Jul;27(7):588-595.

Che-Jui Lee, Hsin-Chien Chen, Cheng-Ping Shih, Yuan-Yung Lin, Chao-Yin Kuo, Shao-Cheng Liu

22

Development of thermosensitive poloxamer 407-based microbubble gel with ultrasound mediation for inner ear drug delivery

Drug Deliv. 2021 Dec;28(1):1256-1271.doi: 10.1080/10717544.2021.1938758.

Ai-Ho Liao, Cheng-Ping Shih, Ming-Wei Li, Yi-Chun Lin, Ho-Chiao Chuang, Chih-Hung Wang

23

Identification of Cancer Hub Gene Signatures Associated with Immune-Suppressive Tumor Microenvironment and Ovatodiolide as a Potential Cancer Immunotherapeutic Agent

Cancers (Basel). 2021 Jul 30;13(15):3847.doi: 10.3390/cancers13153847.

Jia-Hong Chen, Alexander T H Wu, Bashir Lawal, David T W Tzeng, Jih-Chin Lee, Ching-Liang Ho, Tsu-Yi Chao

24

Long-Term Use of Statins Lowering the Risk of Rehospitalization Caused by Ischemic Stroke Among Middle-Aged Hyperlipidemic Patients: A Population-Based Study

Front Pharmacol. 2021 Oct 18;12:741094.

 doi: 10.3389/fphar.2021.741094. eCollection 2021.

25

Ultrasound Microbubbles Enhance the Efficacy of Insulin-Like Growth Factor-1 Therapy for the Treatment of Noise-Induced Hearing Loss

Molecules. 2021 Jun 13;26(12):3626.doi: 10.3390/molecules26123626

Yi-Chun Lin, Yuan-Yung Lin, Hsin-Chien Chen, Chao-Yin Kuo, Ai-Ho Liao, Ying-Liang Chou, Chia-Lien Hung, Cheng-Ping Shih, Chih-Hung Wang 

26

Artificial intelligence-assisted fast screening cervical high grade squamous intraepithelial lesion and squamous cell carcinoma diagnosis and treatment planning

Sci Rep. 2021 Aug 10;11(1):16244.doi: 10.1038/s41598-021-95545-y.

Ching-Wei Wang, Yi-An Liou, Yi-Jia Lin, Cheng-Chang Chang, Pei-Hsuan Chu, Yu-Ching Lee, Chih-Hung Wang, Tai-Kuang Chao

27

Oral tegafur-uracil as a metronomic therapy in stage IVa and IVb cancer of the oral cavity

Am J Otolaryngol. 2021 Nov-Dec;42(6):103156.doi: 10.1016/j.amjoto.2021.103156. Epub 2021 Jun 25.

Wen-Yen Huang, Ching-Liang Ho, Tsu-Yi Chao, Jih-Chin Lee, Jia-Hong Chen

Thyroid Hemiagenesis Accompanying an Ectopic Lingual Thyroid

Ear Nose Throat J. 2021 Sep 16;1455613211036229.doi: 10.1177/01455613211036229.

Kai-Fen Chuang, Jih-Chin Lee, Che-Jui Lee

28

Quantitative spectroscopic comparison of the optical properties of mouse cochlea microstructures using optical coherence tomography at 1.06 µm and 1.3 µm wavelengths

Biomed Opt Express. 2021 Mar 25;12(4):2339-2352.doi: 10.1364/BOE.419378.

Ting-Yen Tsai, Ting-Hao Chen, Hsin-Chien Chen, Chuan-Bor Chueh, Yin-Peng Huang, Yi-Ping Hung, Meng-Tsan Tsai, Bernhard Baumann, Chih-Hung Wang, Hsiang-Chieh Lee

29

Complement Factor I Mutation May Contribute to Development of Thrombotic Microangiopathy in Lupus Nephritis

Front Med (Lausanne). 2021 Feb 5;7:621609.doi: 10.3389/fmed.2020.621609. eCollection 2020.

Min-Hua Tseng, Wen-Lang Fan, Hsuan Liu, Chia-Yu Yang, Jhao-Jhuang Ding, Hwei-Jen Lee, Shih-Ming Huang, Shih-Hua Lin, Jing-Long Huang

30

Association Between Deviated Nasal Septum With Inferior Turbinate Hypertrophy and the Risk of Male Infertility

Am J Rhinol Allergy. 2021 Jan;35(1):17-25.doi: 10.1177/1945892420932485. Epub 2020 Jun 17

Hsin-Chien Chen, Chi-Hsiang Chung, Wu-Chien Chien

31

Convolutional neural network for human cancer types prediction by integrating protein interaction networks and omics data

Sci Rep. 2021 Oct 19;11(1):20691.

 doi: 10.1038/s41598-021-98814-y.

Yi-Hsuan Chuang, Sing-Han Huang, Tzu-Mao Hung, Xiang-Yu Lin, Jung-Yu Lee, Wen-Sen Lai, Jinn-Moon Yang

32

Ultrasound Microbubble-Facilitated Inner Ear Delivery of Gold Nanoparticles Involves Transient Disruption of the Tight Junction Barrier in the Round Window Membrane

Front Pharmacol. 2021 Jun 28;12:689032. doi: 10.3389/fphar.2021.689032. eCollection 2021.

33

Minoxidil-Coated Lysozyme-Shelled Microbubbes Combined With Ultrasound for the Enhancement of Hair Follicle Growth: Efficacy In Vitro and In Vivo

Front Pharmacol. 2021 Apr 27;12:668754.

 doi: 10.3389/fphar.2021.668754. eCollection 2021.

Ai-Ho Liao, Yu-Jhen Huang, Ho-Chiao Chuang, Chih-Hung Wang, Cheng-Ping Shih, Chien-Ping Chiang

34

Genetic co-expression networks contribute to creating predictive model and exploring novel biomarkers for the prognosis of breast cancer

Sci Rep. 2021 Mar 31;11(1):7268.

 doi: 10.1038/s41598-021-84995-z.

35

The Management in Patients With Bilateral Vocal Fold Immobility: 15 Years' Experience at a Tertiary Centre

J Voice. 2021 Mar 19;S0892-1997(21)00087-4.

 doi: 10.1016/j.jvoice.2021.02.019. Online ahead of print.

Wan-Fu Su, Shao-Cheng Liu, Ying-Chieh Hsu