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陳韋良 老年醫學科主任

陳韋良 老年醫學科主任

現職

三軍總醫院家庭暨社區醫學部老年醫學科主任

學位

國防醫學院醫學科學研究所博士
國防醫學院醫學士

教職

國防醫學院醫學系副教授

經歷

中華民國家庭醫學專科醫師
中華民國安寧專科醫師
中華民國老年醫學專科醫師
中華民國職業醫學專科醫師

專長領域

老年醫學
家庭醫學(各類急/慢性疾病)
預防性健 康照護(健康檢查、保健諮詢、疫苗注射、衛生教育)
社區醫學
長期照護
旅遊醫學

研究專長

癌症、CD164、肌少症、肌肉分化、脂肪細胞、心血管代謝疾病、多環芳香烴

得獎紀錄

1. 國防醫學院106年度林可勝先生SCI/SSCI傑出醫學論文獎第1名
2. 三軍總醫院106年優良研究論著個人績效獎第2名
3. 台灣家庭醫學醫學會106年王佳文院長暨李孟智教授優良學術獎助基金獎
4. 三軍總醫院107年優良研究論著個人績效獎第1名

論文著作

癌症與分子醫學 (Cancer and Molecular Biology)
1. Chen YY, Wang CC, Wu WT, Lai CH, Ho CL, Hsu YY, Chen WL. Trajectories of returning to work and its impact on survival in survivors with oral cancer: A 5-year follow-up study. Cancer. 2020 Mar 15;126(6):1225-1234. doi: 10.1002/cncr.32643. Epub 2019 Dec 6.
2. Syu WZ, Hueng DY, Chen WL, Chan JY, Chen SG, Huang SM. Adipose-Derived Neural Stem Cells Combined with Acellular Dermal Matrix as a Neural Conduit Enhances Peripheral Nerve Repair. Cell Transplant. 2019 Sep-Oct;28(9-10):1220-1230. doi: 10.1177/0963689719853512. Epub 2019 May 31.
3. Wang CC, Hueng DY, Huang AF, Chen WL, Huang SM, Yi-Hsin Chan J. CD164 regulates proliferation, progression, and invasion of human glioblastoma cells. Oncotarget. 2019 Mar 12;10(21):2041-2054. doi: 10.18632/oncotarget.26724. eCollection 2019 Mar 12.
4. Wu LW, Chen WL, Huang SM, Chan JY. Platelet-derived growth factor-AA is a substantial factor in the ability of adipose-derived stem cells and endothelial progenitor cells to enhance wound healing. FASEB J. 2019 Feb;33(2):2388-2395. doi: 10.1096/fj.201800658R. Epub 2018 Sep 28.
5. Chen JH, Chen WL, Chan JY, Chen YW, Peng YJ, Cheng MF, Lin CS. Overexpression of CD164 in oral cavity squamous cell carcinoma predicts a favourable prognosis. Oncol Lett. 2017 Nov;14(5):6103-6108. doi: 10.3892/ol.2017.6966. Epub 2017 Sep 15.
6. Chen WL, Huang AF, Huang SM, Ho CL, Chang YL, Chan JY. CD164 promotes lung tumor-initiating cells with stem cell activity and determines tumor growth and drug resistance via Akt/mTOR signaling. Oncotarget. 2016 Aug 9;8(33):54115-54135.

肌肉分化與肌少症 (Muscle and Sarcopenia)
1. Peng TC, Chen WL, Wu LW, Chang YW, Kao TW. The Prevalence of Frailty by the FRAIL-NH Scale in Taiwan Nursing Home Residents. J Nutr Health Aging. 2020;24(5):507-511. doi: 10.1007/s12603-020-1350-3.

2. Peng TC, Chen WL, Wu LW, Chang YW, Kao TW. Sarcopenia and cognitive impairment: A systematic review and meta-analysis. Clin Nutr. 2019 Dec 17. pii: S0261-5614(19)33200-5. doi: 10.1016/j.clnu.2019.12.014.
3. Chiu HT, Shih MT, Chen WL. Examining the association between grip strength and testosterone. Aging Male. 2019 Jul 3:1-8.
4. Chen YY, Fang WH, Wang CC, Kao TW, Yang HF, Wu CJ, Sun YS, Wang YC, Chen WL. Fat-to-muscle ratio is a useful index for cardiometabolic risks: A population-based observational study. PLoS One. 2019 Apr 9;14(4):e0214994. doi: 10.1371/journal.pone.0214994. eCollection 2019.
5. Chen YY, Kao TW, Chou CW, Wu CJ, Yang HF, Lai CH, Wu LW, Chen WL. Exploring the Link between Serum Phosphate Levels and Low Muscle Strength, Dynapenia, and Sarcopenia. Sci Rep. 2018 Feb 23;8(1):3573.
6. Chen YY, Fang WH, Wang CC, Kao TW, Chang YW, Yang HF, Wu CJ, Sun YS, Chen WL. Examining the Associations among Fibrocystic Breast Change, Total Lean Mass, and Percent Body Fat. Sci Rep. 2018 Jun 15;8(1):9180.
7. Peng TC, Wu LW, Chen WL, Liaw FY, Chang YW, Kao TW. Nonalcoholic fatty liver disease and sarcopenia in a Western population (NHANES III): The importance of sarcopenia definition. Clin Nutr. 2017 Dec 8. pii: S0261-5614(17)31419-X.
8. Sun YS, Kao TW, Chang YW, Fang WH, Wang CC, Wu LW, Yang HF, Liaw FY, Chen WL. Calf Circumference as a Novel Tool for Risk of Disability of the Elderly Population. Sci Rep. 2017 Nov 27;7(1):16359.

多環芳香烴 (Polycyclic Aromatic Hydrocarbons)
1. Chen YY, Wang CC, Kao TW, Yang HF, Sun YS, Chen WL. Detrimental Association between Quadriceps Strength and Exposure to Polycyclic Aromatic Hydrocarbons in Elderly Adults. Appl Physiol Nutr Metab. 2020 Jan 18. doi: 10.1139/apnm-2019-0808. [Epub ahead of print]
2. Chen YY, Kao TW, Wang CC, Wu CJ, Chou YC, Chen WL. Association between Polycyclic Aromatic Hydrocarbons Exposure and Bone Turnover in Adults. Eur J Endocrinol. 2019 Dec 1. pii: EJE-19-0750.R1. doi: 10.1530/EJE-19-0750. [Epub ahead of print]
3. Chou CW, Chen YY, Wang CC, Kao TW, Wu CJ, Chen YJ, Zhou YC, Chen WL. Urinary biomarkers of polycyclic aromatic hydrocarbons and the association with hearing threshold shifts in the United States adults. Environ Sci Pollut Res Int. 2020 Jan;27(1):562-570. doi: 10.1007/s11356-019-06883-4. Epub 2019 Dec 5.
4. Chen YY, Kao TW, Wang CC, Chen YJ, Wu CJ, Lai CH, Chen WL. Exposure to polycyclic aromatic hydrocarbons and risk of disability among an elderly population. Environ Sci Pollut Res Int. 2019 Apr;26(11):10719-10726. doi: 10.1007/s11356-019-04498-3. Epub 2019 Feb 18.


心血管代謝疾病 (Cardiometabolic Risks)
1. Chen YY, Fang WH, Wang CC, Kao TW, Chang YW, Yang HF, Wu CJ, Sun YS, Chen WL. Characterization of Cardiometabolic Risks in Different Combination of Anthropometric Parameters and Percentage Body Fat. Sci Rep. 2019 Oct 1;9(1):14104. doi: 10.1038/s41598-019-50606-1.
2. Wu CJ, Kao TW, Chang YW, Peng TC, Wu LW, Yang HF, Chen WL. Does the Additional Component of Calf Circumference Refine Metabolic Syndrome in Correlating With Cardiovascular Risk? J Clin Endocrinol Metab. 2018 Mar 1;103(3):1151-1160.
3. Wu CJ, Kao TW, Yang HF, Sun YS, Chen YJ, Wang CC, Lai CH, Chen WL. Predictability of cardiorespiratory fitness on the risk of developing metabolic syndrome and diabetes mellitus in Taiwan adults: Preliminary analysis of a cohort study. Obes Res Clin Pract. 2018 Jul 24. pii: S1871-403X(18)30017-6.
4. Zhou YC, Fang WH, Kao TW, Wang CC, Chang YW, Peng TC, Wu CJ, Yang HF, Chan JY, Chen WL. Exploring the association between thyroid- stimulating hormone and metabolic syndrome: A large population-based study. PLoS One. 2018 Jun 21;13(6):e0199209.
5. Chen YY, Kao TW, Yang HF, Chou CW, Wu CJ, Lai CH, Sun YS, Wang CC, Chen WL. The association of uric acid with the risk of metabolic syndrome, arterial hypertension or diabetes in young subjects- An observational study. Clin Chim Acta. 2018 Mar;478:68-73.

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